Anti-Synaptopodin/SYNPO Antibody

Product Name

Anti-Synaptopodin/SYNPO Antibody

View all Synaptopodin Antibodies

SKU/Catalog Number

RP1069

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Synaptopodin/SYNPO Antibody catalog # RP1069. Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Synaptopodin/SYNPO Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1069)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Synaptopodin, different from the related mouse sequence by one amino acid, and identical to the related rat sequence.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

RP1069 is reactive to SYNPO in Human, Mouse

Applications

RP1069 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

99 kDa

Calculated molecular weight

99.463kDa

Background of Synaptopodin

Synaptopodin is also known as SYNPO. The spine apparatus (SA) is a specialized form of endoplasmic reticulum (ER) that is found in a subpopulation of dendritic spines in central neurons. The SA consists of a series of stacked discs that are thought to be connected to each other and to the dendritic system of ER-tubules. The actin binding protein synaptopodin (which has originally been described in podocytes of the kidney) is an essential component of the SA. Mice that lack the gene for synaptopodin do not form a spine apparatus. The SA is believed to play a critical role in learning and memory. In summary, an important function of the spine apparatus is the regulation of plasticity at individual synapses, a process known as metaplasticity. The International Radiation Hybrid Mapping Consortium mapped the SYNPO gene to chromosome 5.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse

Validation Images & Assay Conditions

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Anti-Synaptopodin antibody, RP1069, Western blotting
All lanes: Anti Synaptopodin (RP1069) at 0.5ug/ml
Lane 1: Mosue Brain Tissue Lysate at 50ug
Lane 2: U87 Whole Cell Lysate at 40ug
Lane 3: HEPG2 Whole Cell Lysate at 40ug
Lane 4: 293T Whole Cell Lysate at 40ug
Predicted bind size: 99KD
Observed bind size: 99KD

Gene/Protein Information For SYNPO (Source: Uniprot.org, NCBI)

Alternative Names

KIAA1029; Synaptopodin; SYNPO SYNPO synaptopodin synaptopodin

For more info on SYNPO, check out the SYNPO Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SYNPO: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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